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<\/a><\/p>\nOf all the content posted on this site, this one has been the most heavily suppressed on ALL<\/strong> social media platforms, to the degree it wasn\u2019t even seen via direct private messages to people I know for a fact want this information. Don\u2019t know how the “powers that be” suppressed it in DM’s but they did and the lack of traffic has forced me to re-up it after being sandbagged for a month.<\/p>\n There is no<\/strong> conspiracy, no<\/strong> conjecture in the content below. This information is FACT, it\u00a0predates all the stories<\/strong> that are now headlining from multiple sites and news outlets, like this one from FN<\/a>\u00a0(in other words STR was the first to report on the origin). Many of those stories you\u2019re seeing are based on a 2018 cable sent to the State Dept<\/a> to papers done AFTER the virus went global.<\/p>\n Researchers in the US, Switzerland<\/u> and China<\/strong> published this study<\/a> titled A SARS-like cluster of circulating bat coronaviruses shows potential for human emergence<\/i>\u00a0on\u00a0Nov 9, 2015<\/strong>, to “examine the emergence potential (that is, the potential to infect humans) of circulating bat CoVs..”<\/i>. The purpose of the study in a nutshell is to identify possible new pathogens as a result of cross-species transmission, since SARS, MERS and other pathogens have had large impact on humans causing illness, death and economic disruption, with the intent to “identify and prepare for future prepandemic viruses”.<\/i> So to be clear these scientists did this study for the good of people, nothing nefarious is going on.<\/p>\n Okay, now they* engineered a bug….<\/p>\n “Abstract<\/b><\/p>\n The emergence of severe acute respiratory syndrome coronavirus (SARS-CoV) and Middle East respiratory syndrome (MERS)-CoV underscores the threat of cross-species transmission events leading to outbreaks in humans. Here we examine the disease potential of a SARS-like virus, SHC014-CoV, which is currently circulating in Chinese horseshoe bat populations<\/span>1<\/a><\/span>. Using the SARS-CoV reverse genetics system<\/span>2<\/a><\/span>, <\/span>we generated<\/b> and characterized a chimeric virus expressing the spike of bat coronavirus <\/span><\/u>SHC014 in a mouse-adapted SARS-CoV backbone. The results indicate that group 2b viruses encoding the SHC014 spike in a wild-type backbone can efficiently use multiple orthologs of the SARS receptor human angiotensin converting enzyme II (ACE2), <\/span>replicate efficiently in primary human airway cells and achieve\u00a0<\/span><\/u><\/span>in vitro<\/span><\/u><\/i>\u00a0titers equivalent to epidemic strains of SARS-CoV<\/span><\/u>. Additionally,\u00a0<\/span><\/span>in vivo<\/i>\u00a0experiments demonstrate replication of the chimeric virus in mouse lung with notable pathogenesis. Evaluation of available SARS-based immune-therapeutic and prophylactic modalities revealed poor efficacy; both monoclonal antibody and vaccine approaches failed to neutralize and protect from infection with CoVs using the novel spike protein. On the basis of these findings, we synthetically re-derived an infectious full-length SHC014 recombinant virus and demonstrate robust viral replication both\u00a0<\/span>in vitro<\/i>\u00a0and\u00a0<\/span>in vivo<\/i>. <\/span>Our work suggests a potential risk of SARS-CoV re-emergence from viruses currently circulating in bat populations.<\/span><\/u><\/span><\/span><\/p>\n Main<\/b><\/p>\n The emergence of SARS-CoV heralded a new era in the cross-species transmission of severe respiratory illness with globalization leading to rapid spread around the world and massive economic impact<\/u><\/span>3<\/a>,4<\/a><\/span>. Since then, several strains\u2014including influenza A strains H5N1, H1N1 and H7N9 and MERS-CoV\u2014have emerged from animal populations, causing considerable disease, mortality and economic hardship for the afflicted regions<\/span>5<\/a><\/span>. Although public health measures were able to stop the SARS-CoV outbreak<\/span>4<\/a><\/span>, <\/span>recent metagenomics studies have identified sequences of closely related SARS-like viruses circulating in Chinese bat populations that may pose a future threat<\/span><\/b><\/u><\/span>1<\/a>,6<\/a><\/span>. However, sequence data alone provides minimal insights to identify and prepare for future prepandemic viruses. Therefore, <\/span>to examine the emergence potential (that is, <\/span>the potential to infect humans<\/b>) of circulating bat CoVs, <\/span>we built a chimeric virus<\/span><\/b> encoding a novel, zoonotic CoV spike protein\u2014from the RsSHC014-CoV sequence that was isolated from Chinese horseshoe bats<\/b><\/span><\/u><\/span>1<\/span><\/u><\/a><\/span>\u2014in the context of the SARS-CoV mouse-adapted backbone. The <\/span>hybrid virus<\/b><\/span> allowed us to evaluate the ability of the novel spike protein to cause disease independently of other necessary adaptive mutations<\/b> in its natural backbone.<\/span><\/u> Using this approach, we characterized CoV infection mediated by the SHC014 spike protein in primary human airway cells and\u00a0<\/span><\/span>in vivo<\/i>, and tested the efficacy of available immune therapeutics against SHC014-CoV. Together, the strategy translates metagenomics data to help predict and prepare for future emergent viruses.<\/span>“<\/span><\/span><\/p><\/blockquote>\n ….so the question is did the hybrid bug, multiple labs*<\/b> were working on (including Key Laboratory of Special Pathogens and Biosafety, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, China), get loose and is that bug COVID-19?? To be clear labs in the US and Switzerland were involved in this study too, so do what you will with the information. But, it should now make sense why the Chinese are pointing the finger back at the US govt for causing the COVID-19 pandemic. The study is legit, we just need to know where the bug came from and is it in fact the hybrid or something new!?<\/p>\n
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\nFACT: We have a novel virus on the loose at pandemic level, and it started in the province where a BSL4 lab is located which was involved in the study of novel CoV virus!<\/p>\n
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